Not sorta funny at all: H5N1

That's a name you will remember.

Bird flu hasn't gone away. The discovery, announced last week, that the H5N1 bird flu virus is widespread in cats in locations across Indonesia has refocused attention on the danger that the deadly virus could be mutating into a form that can infect humans far more easily.

In the first survey of its kind, an Indonesian scientist has found that in areas where there have been outbreaks of H5N1 in poultry and humans, 1 in 5 cats have been infected with the virus, and survived. This suggests that as outbreaks continue to flare across Asia and Africa, H5N1 will have vastly more opportunities to adapt to mammals than had been supposed.

And bear in mind, this influenza is really nasty. Some studies suggest its 10 times as potent as the Spanish flu [H1N1] that killed millions of people in 1918.

Scientists might have identified one of the reasons why the bird flu virus H5N1 is so deadly to humans. A study published today in the open access journal Respiratory Research reveals that, in human cells, the virus can trigger levels of inflammatory proteins more than 10 times higher than the common human flu virus H1N1. This might contribute to the unusual severity of the disease caused by H5N1 in humans, which can escalate into life-threatening pneumonia and acute respiratory distress.

Michael Chan and colleagues from the University of Hong Kong and collaborators in Vietnam, studied the levels of a subset of the pro-inflammatory proteins called 'cytokines' and 'chemokines', induced by the virus H5N1 in human lung cells, in vitro. The authors compared protein levels induced by strains of the H5N1 virus that had appeared in Hong Kong in 1997 (H5N1/97) and Vietnam in 2004 (H5N1/04), with levels induced by the human flu virus H1N1.

If you still doubt how nasty bird flu might be, check this out and remember bird flu is worse.

The "Spanish" flu pandemic of 1918 and 1919 caused the deaths of 20-50 million people worldwide including up to 675,000 in the U.S. While only about 1% of those infected with the virus died, it became one of the deadliest viruses ever known to man. The 1918 flu has been described as capable of sickening and killing a person on the same day. The virus is an H1N1 type A influenza. Symptoms of infection were similar to, but more severe than typical, seasonal flu.

Keep pressure on Congress to be prepared. We don't need another "Katrina".

Hey, is Katrina now synonymous with disaster? It should be.

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